Jan Steinkühler


A lipid bilayer vesicle with nanotubes on the inside. Scale bar 5um.

View My GitHub Profile

Hello, I’m a researcher in the field of biophysics, soft matter and synthetic biology. In the past years my research was focused on the understanding, assembly and applications of biomembranes. I obtained my PhD in the Dimova Lab. After my first postdoc with Reinhard Lipowsky, I’m currently working with Neha Kamat. I mostly work experimentally and use software tools to analyze and understand data acquired in the lab. Recently I have developed some interest in using computer simulations. Over time I will upload more tools and scripts I have used.

Calculate area, volume and adhesion energies from confocal images of adhering vesicles

Full publication list at Google Scholar, CV, e-mail and twitter @ja_steinkuehler.

First author publications

  1. Superelasticity of Plasma-and Synthetic Membranes Resulting from Coupling of Membrane Asymmetry, Curvature, and Lipid Sorting, Steinkühler, J., Fonda, P., Bhatia, T., Zhao, Z., Leomil, F. S., Lipowsky, R., & Dimova, R. Advanced Science, 2102109 (2021) Full Text
  2. Energy Dissipation at Interfaces Drives Multicompartment Remodeling, J. Steinkühler, N.H. Kamat (2020) Chem Full Text
  3. Controlled division of cell-sized vesicles by low densities of membrane-bound proteins, J. Steinkühler, R.L. Knorr, Z. Zhao, T. Bhatia, S.M. Bartelt, S. Wegner, R. Dimova and R. Lipowsky, Nature Communications, 11(1), 1-11 (2020) Full Text Press release
  4. Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density, J. Steinkühler, E. Sezgin, I. Urbančič, C. Eggeling, R. Dimova Communications Biology, Volume 2, 337 2019 Full Text
  5. Membrane fluctuations and acidosis regulate cooperative binding of “marker of self” CD47 with macrophage checkpoint receptor SIRPα, J. Steinkühler, B. Różycki, C. Alvey, R. Lipowsky, T.R. Weikl, R. Dimova., D. E. Discher J Cell Sci, 132(4) 2019 Full Text with Featured first-author interview
  6. Light guided motility of a minimal synthetic cell, S. M. Bartelt*, J. Steinkühler*, R. Dimova, S. V. Wegner *equal contribution Nano Letters, 18(11), pp.7268-7274, 2018 Full Text
  7. Charged giant unilamellar vesicles prepared by electroformation exhibit nanotubes and transbilayer lipid asymmetry, J Steinkühler, P. De Tillieux, R.L. Knorr, R. Lipowsky, R. Dimova Scientific Reports 8 (1), 11838, 2018 Full Text
  8. Modulating Vesicle Adhesion by Electric Fields, J. Steinkühler, J. Agudo-Canalejo, R. Lipowsky, R. Dimova Biophysical Journal 111 (7), 1454-1464, 2016 Full Text
  9. Characterization of Double Layer Alterations Induced by Charged Particles and Protein–Membrane Interactions Using Contactless Impedance Spectroscopy, J. Steinkühler, V. Charwat, L. Richter, P. Ertl The Journal of Physical Chemistry B 116 (35), 10461-10469, 2012 Full Text